Vaccine Safety

Post-licensure surveillance of adverse events following immunisation (AEFI) is an important component of any national immunisation program and essential to maintaining the confidence of the general public and immunisation providers in the National Immunisation Program.

NCIRS plays a lead role in a range of important vaccine safety activities, many of which are collaborations with other organisations.

NSW Immunisation Specialist Service (NSWISS) which provides a drop-in immunisation clinic and a specialist clinic at The Children’s Hospital at Westmead, and a telephone advice line to support immunisation providers in NSW.

Analysis and reporting of the Therapeutic Goods Administration (TGA) national surveillance data, collected by passive reporting from immunisation providers, parents, pharmaceutical companies or other parties.

AusVaxSafety active surveillance for adverse events following influenza immunisation in children less than 5 years of age and pertussis booster immunisations in children aged 12 months to less than 7 years of age.

Research studies on febrile seizures after vaccination and adverse events following Q fever vaccination.

Active, hospital-based surveillance for intussusception using the Paediatric Active Enhanced Disease Surveillance (PAEDS) network.

The NCIRS vaccine safety fact sheets provide information on specific issues. These fact sheets have been developed primarily for immunisation providers, but may also be of interest to members of the public.